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Three-dimensional
confocal fluorescent images with unsurpassed resolution and
contrast-now obtainable at a minimum cost for use in broad
bio-research applications
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Nikon proudly introduces
a universal confocal microscope system that is ultra-compact
and lightweight, yet provides confocal images of the highest
quality in its class.
With the C1, confocal microscopy is now a mainstream technique
affordable by all. |
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Highest quality optical performance
A successful fusion of Nikon's optical and electronics technologies,
the C1's resolution, contrast, and fluorescent image brightness
are all top-class and "State of the Art." Image sizes of up
to 2K by 2K at 12 bit image depth can be easily scanned.
Interchangeable filters
Changing the filter to match the fluorescent dyes you want
to use is simple and quick, enabling the use of the latest
probes or dyes available today.
3-channel simultaneous detection
The C1 supports almost any imaging technique required today,
including simultaneous 3-channel fluorescence, 3-channel plus
DIC, time-lapse recording, and spatial analysis.
Modular design saves space and facilitates upgrading
All main components are modular including the laser box, scanner
head, and detector module, saving desk space and allowing
easy upgrades and maintenance.
Intuitive software promotes multifaceted microscopic analysis
The C1's Graphical User Interface (GUI) is extremely simple
and intuitive. From the time of initial use, you may never
need to refer to the manual for typical operation.
Easy to configure, easy to operate
Each of the modules is pre-calibrated, eliminating the need
for calibration during setup. Just connect the modules you
need, and you are ready for optimal image capture.
Compact design
With a small footprint, the C1 does not get in the way of
other lab equipment. Consequently, there is plenty of work
space left around the microscope. |
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| Unprecedented
image quality |
Why are the C1's images so good?
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Stray light, which is
usually generated in the scanner head and common in
some other designs, is thoroughly eliminated, while
reflection loss on the I/O ends of the optical fiber
is minimized. This makes it possible to obtain images
with extremely high contrast and photon efficiency. |
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 Fluorescence transmission
efficiency has been dramatically improved to obtain
fluorescent images 3 times brighter than previous
Nikon models. This, coupled with the use of high quantum-efficiency
photomultiplier tubes, gives clear, sharp images even
with fluorescent specimens that in the past were too
dim to observe. |
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Signal-to-noise ratio
has been increased 7-fold (compared to previous Nikon
models), resulting in a significantly improved image
quality. |
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12-bit digitization pixel
depth ensures the quality, dynamic range and sensitivity
that is required of a 4-megapixel image . |
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Universal scanner head
The scanner head can be easily mounted on either upright or
inverted microscopes to support a wide range of applications. |
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| C1
system configured with E600 microscope |
C1
system configured with TE2000 microscope |
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 Various laser types
The wider range of excitation light wavelengths facilitating
the use of an increased number of fluorochromes in research
has increased the demand for the number of lasers available
on the market. The C1 comes with a series of lasers supporting
almost every fluorescent dye used in research today. |
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Wide choices of fluorochromes
Besides the excitation lasers, a full selection of emission
filters are available to support a wide range of fluorescence
observation needs. The detection module is supplied with appropriate
dichroic mirrors, allowing simultaneous 3-color observation
of fluorescence images of specimens prepared for 3-color imaging
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| Operation is
a breeze-and customizing just as simple |
| Live images can be captured with ease |
 All settings and procedures required for live
image capture-fundamentals in confocal microscopy-can be viewed
in a single window, eliminating the need for the operator
to switch between many windows. The operation panel gives
you an at-a-glance picture of all important settings including
scan mode, scan speed, pixel size, zoom/pan, PMT settings,
pinhole, shutter, and color image look-up table. With the
C1, scanning modes are expanded from 2D (XY, YZ, XZ), to 3D
(XYZ, Xyt), and even further to 4-dimensional (XYZt) scans. |
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Time-lapse recording is also a simple
matter
All required procedures for time-lapse recording, including
the setting of inter-cycle times, frame intervals, and the
number of images to be captured can be provided in a single
window for quick, easy operation. Image capture via sync-control
from automated accessories or connected electrophysiology
equipment is also possible. |
data
sheet (*.pdf)
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